TOXIC EFFECTS OF ENDOSULFAN AN AGRICULTURAL PESTICIDE ON BLOOD CHEMISTRY OF FRESH WATER CATFISH PANGASIUS

Abstract

Toxicologists did some notable histopathological studies in fishes to know the safe dose of pesticides for the different tissues in a fish and in assessing the water quality. It has already found conclusively true that changes in blood chemistry can be very important indicator of the toxic effect of pesticides. In the present study in sublethal concentration of Endosulfan for different intervals of day’s significant decrease in large lymphocytes accompanied by significant increase in small lymphocytes was recorded. The toxic effects of 96-h LC50 Endosulfan are significant decrease in erythrocyte surface area. THC, Hb and THC but significant increase in ESR, TLC and coagulation time. The toxic effects of sublethal Endosulfan are- significant decrease in erythrocyte surface area, TEC, Hb, PCV% and CT and significant increase in ESR, TLC and THC. The toxic effect of Endosulfan was very much evident in different blood parameters. TEC, Hb Level, PCV%, MCH and MCHC decreased significantly but ESR value showed significant increase from 3.31 mm/h to 5.47 mm/h. TEC, Hb level, PCV% all showed significant decrease in their values. MCV and MCH showed significant decrease but the MCHC decreased only slightly. ESR increased significantly from 3.11 mm/h to 5.52 mm/h. Keywords: Sublethal, Pesticide, Pangasius, Endosulfan, Thrombocytes.